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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
6.67
Human Site:
S2377
Identified Species:
12.22
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S2377
Q
Q
E
T
E
P
P
S
A
L
Q
S
P
L
G
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
S2287
Q
F
Q
V
S
S
S
S
L
A
R
I
F
Q
L
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S2404
Q
Q
E
T
E
P
P
S
A
L
Q
S
P
L
G
Dog
Lupus familis
XP_537788
2395
264756
A2329
H
L
F
R
P
R
P
A
P
T
E
L
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
P2376
V
E
Q
Q
E
A
E
P
S
S
L
P
S
P
L
Rat
Rattus norvegicus
Q9ESR9
2434
270910
P2376
V
E
Q
Q
E
A
E
P
S
T
L
P
S
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
E2209
N
K
K
R
L
H
I
E
D
Y
S
V
S
Q
T
Chicken
Gallus gallus
XP_422330
2276
256293
K2219
F
R
L
I
I
S
N
K
E
N
L
Y
I
E
E
Frog
Xenopus laevis
NP_001089022
2363
267334
S2303
R
V
F
Q
L
L
I
S
N
K
D
S
L
N
I
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
E2211
N
K
E
Q
L
H
I
E
D
Y
S
V
S
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
D1647
Q
I
P
K
E
K
E
D
C
W
S
A
K
F
E
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
D1856
I
K
G
V
Q
Q
K
D
E
K
Q
V
V
T
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
F1824
S
S
F
P
G
A
T
F
K
S
C
N
G
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
13.3
100
6.6
N.A.
6.6
6.6
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
26.6
100
20
N.A.
26.6
26.6
N.A.
13.3
6.6
20
13.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
24
0
8
16
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
16
16
0
8
0
0
0
0
% D
% Glu:
0
16
24
0
39
0
24
16
16
0
8
0
0
8
16
% E
% Phe:
8
8
24
0
0
0
0
8
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
16
% G
% His:
8
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
8
0
24
0
0
0
0
8
8
0
8
% I
% Lys:
0
24
8
8
0
8
8
8
8
16
0
0
8
0
0
% K
% Leu:
0
8
8
0
24
8
0
0
8
16
24
8
8
24
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
8
0
8
8
0
8
0
8
0
% N
% Pro:
0
0
8
8
8
16
24
16
8
0
0
16
16
16
0
% P
% Gln:
31
16
24
31
8
8
0
0
0
0
24
0
0
24
0
% Q
% Arg:
8
8
0
16
0
8
0
0
0
0
8
0
8
0
0
% R
% Ser:
8
8
0
0
8
16
8
31
16
16
24
24
31
0
8
% S
% Thr:
0
0
0
16
0
0
8
0
0
16
0
0
0
8
16
% T
% Val:
16
8
0
16
0
0
0
0
0
0
0
24
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _